Home · CAZyme Families

CAZyme Families 522 families and subfamilies · 201,960 genes across 148,384 CGCs · CAZy classes GH / PL / CE

GH Glycoside Hydrolases · 406 families and subfamilies · 172,118 genes · 126,068 CGCs

Family	EC numbers	Activity (EC name)	Genes	CGCs
GH1	3.2.1.18, 3.2.1.21, 3.2.1.23, 3.2.1.25, 3.2.1.31 (+24 more)	exo-α-sialidase, β-glucosidase, β-galactosidase, β-mannosidase (+23 more)	4,170	4,065
GH2_1	3.2.1.23, 3.2.1.108, 3.2.1.-	β-galactosidase, lactase	718	692
GH2_2	3.2.1.23, 3.2.1.31	β-galactosidase, β-glucuronidase	281	275
GH2_3	3.2.1.31, 3.2.1.128, 3.2.1.-	β-glucuronidase, glycyrrhizinate β-glucuronidase	132	131
GH2_4	3.2.1.31, 3.2.1.-	β-glucuronidase	288	288
GH2_5	3.2.1.23	β-galactosidase	106	105
GH2_6	3.2.1.-	—	165	164
GH2_7	3.2.1.23	β-galactosidase	105	86
GH2_8	3.2.1.31	β-glucuronidase	21	21
GH2_9	3.2.1.23	β-galactosidase	8	8
GH2_10	3.2.1.23, 3.2.1.108, 3.2.1.-	β-galactosidase, lactase	1,501	1,460
GH2_11	3.2.1.23, 3.2.1.-	β-galactosidase	113	108
GH2_12	—	—	34	34
GH2_13	3.2.1.25	β-mannosidase	1,070	1,058
GH2_14	3.2.1.23	β-galactosidase	35	35
GH2_15	3.2.1.21, 3.2.1.23, 3.2.1.52	β-glucosidase, β-galactosidase, β-N-acetylhexosaminidase	223	223
GH2_16	3.2.1.165	exo-1,4-β-D-glucosaminidase	118	117
GH2_17	3.2.1.152	mannosylglycoprotein endo-β-mannosidase	109	106
GH2_18	3.2.1.55, 3.2.1.146	non-reducing end α-L-arabinofuranosidase, β-galactofuranosidase	432	415
GH2_19	3.2.1.23, 3.2.1.55, 3.2.1.145, 3.2.1.146	β-galactosidase, non-reducing end α-L-arabinofuranosidase, galactan 1,3-β-galactosidase, β-galactofuranosidase	416	409
GH2_20	3.2.1.23	β-galactosidase	204	183
GH2_21	3.2.1.31	β-glucuronidase	38	38
GH2_22	3.2.1.37	xylan 1,4-β-xylosidase	13	13
GH2_23	3.2.1.23	β-galactosidase	11	11
GH2	3.2.1.21, 3.2.1.23, 3.2.1.25, 3.2.1.31, 3.2.1.37 (+9 more)	β-glucosidase, β-galactosidase, β-mannosidase, β-glucuronidase (+9 more)	6,285	5,815
GH3	3.2.1.6, 3.2.1.8, 3.2.1.21, 3.2.1.23, 3.2.1.31 (+18 more)	endo-1,3(4)-β-glucanase, endo-1,4-β-xylanase, β-glucosidase, β-galactosidase (+17 more)	13,331	12,844
GH4	3.2.1.20, 3.2.1.22, 3.2.1.67, 3.2.1.86, 3.2.1.122 (+1 more)	α-glucosidase, α-galactosidase, galacturonan 1,4-α-galacturonidase, 6-phospho-β-glucosidase (+2 more)	2,108	2,018
GH5_1	3.2.1.4, 3.2.1.73, 3.2.1.74	cellulase, licheninase, glucan 1,4-β-glucosidase	111	110
GH5_2	3.2.1.4, 3.2.1.8, 3.2.1.73, 3.2.1.132	cellulase, endo-1,4-β-xylanase, licheninase, chitosanase	287	283
GH5_4	3.2.1.4, 3.2.1.6, 3.2.1.8, 3.2.1.73, 3.2.1.78 (+3 more)	cellulase, endo-1,3(4)-β-glucanase, endo-1,4-β-xylanase, licheninase (+3 more)	179	168
GH5_5	3.2.1.4	cellulase	117	113
GH5_7	3.2.1.25, 3.2.1.78	β-mannosidase, mannan endo-1,4-β-mannosidase	213	212
GH5_8	3.2.1.78	mannan endo-1,4-β-mannosidase	102	100
GH5_10	3.2.1.37, 3.2.1.78	xylan 1,4-β-xylosidase, mannan endo-1,4-β-mannosidase	40	40
GH5_12	3.2.1.21, 3.2.1.45, 3.2.1.104	β-glucosidase, glucosylceramidase, steryl-β-glucosidase	46	46
GH5_13	3.2.1.55, 3.2.1.146	non-reducing end α-L-arabinofuranosidase, β-galactofuranosidase	382	378
GH5_17	3.2.1.78	mannan endo-1,4-β-mannosidase	2	2
GH5_18	3.2.1.21, 3.2.1.25	β-glucosidase, β-mannosidase	34	34
GH5_19	3.2.1.25, 3.2.1.-	β-mannosidase	66	66
GH5_21	3.2.1.8	endo-1,4-β-xylanase	20	17
GH5_22	3.2.1.4, 3.2.1.8, 3.2.1.37	cellulase, endo-1,4-β-xylanase, xylan 1,4-β-xylosidase	37	37
GH5_24	—	—	9	9
GH5_25	3.2.1.4, 3.2.1.8, 3.2.1.78	cellulase, endo-1,4-β-xylanase, mannan endo-1,4-β-mannosidase	206	205
GH5_26	3.2.1.4, 3.2.1.6, 3.2.1.73	cellulase, endo-1,3(4)-β-glucanase, licheninase	64	64
GH5_27	3.2.1.123	endoglycosylceramidase	11	11
GH5_28	3.2.1.123	endoglycosylceramidase	59	59
GH5_29	3.2.1.46, 3.2.1.123	galactosylceramidase, endoglycosylceramidase	13	13
GH5_34	3.2.1.-	—	19	18
GH5_35	3.2.1.8	endo-1,4-β-xylanase	21	20
GH5_36	3.2.1.78	mannan endo-1,4-β-mannosidase	67	66
GH5_37	3.2.1.4, 3.2.1.6, 3.2.1.73, 3.2.1.74, 3.2.1.91	cellulase, endo-1,3(4)-β-glucanase, licheninase, glucan 1,4-β-glucosidase (+1 more)	9	9
GH5_38	3.2.1.4, 3.2.1.8, 3.2.1.73	cellulase, endo-1,4-β-xylanase, licheninase	24	24
GH5_39	3.2.1.4	cellulase	70	68
GH5_40	3.2.1.78	mannan endo-1,4-β-mannosidase	22	20
GH5_41	3.2.1.78	mannan endo-1,4-β-mannosidase	79	75
GH5_42	—	—	63	63
GH5_43	3.2.1.21	β-glucosidase	9	9
GH5_44	3.2.1.23, 3.2.1.58	β-galactosidase, glucan 1,3-β-glucosidase	5	5
GH5_45	3.2.1.21, 3.2.1.55	β-glucosidase, non-reducing end α-L-arabinofuranosidase	23	23
GH5_46	3.2.1.4, 3.2.1.75	cellulase, glucan endo-1,6-β-glucosidase	421	415
GH5_47	3.2.1.39, 3.2.1.75	glucan endo-1,3-β-D-glucosidase, glucan endo-1,6-β-glucosidase	54	51
GH5_48	3.2.1.52, 3.2.1.132	β-N-acetylhexosaminidase, chitosanase	46	45
GH5_51	—	—	7	7
GH5_53	3.2.1.74	glucan 1,4-β-glucosidase	21	20
GH5_54	—	—	16	15
GH5_55	3.2.1.4, 3.2.1.78	cellulase, mannan endo-1,4-β-mannosidase	13	13
GH5_56	—	—	3	3
GH5_57	3.2.1.78	mannan endo-1,4-β-mannosidase	13	12
GH5	3.2.1.4, 3.2.1.6, 3.2.1.8, 3.2.1.21, 3.2.1.23 (+23 more)	cellulase, endo-1,3(4)-β-glucanase, endo-1,4-β-xylanase, β-glucosidase (+23 more)	3,263	3,048
GH6	3.2.1.4, 3.2.1.8, 3.2.1.73, 3.2.1.91	cellulase, endo-1,4-β-xylanase, licheninase, cellulose 1,4-β-cellobiosidase (non-reducing end)	219	214
GH8	3.2.1.4, 3.2.1.6, 3.2.1.8, 3.2.1.32, 3.2.1.73 (+2 more)	cellulase, endo-1,3(4)-β-glucanase, endo-1,4-β-xylanase, endo-1,3-β-xylanase (+3 more)	644	640
GH9	3.2.1.4, 3.2.1.6, 3.2.1.8, 3.2.1.73, 3.2.1.74 (+4 more)	cellulase, endo-1,3(4)-β-glucanase, endo-1,4-β-xylanase, licheninase (+4 more)	928	902
GH10	3.2.1.4, 3.2.1.8, 3.2.1.32, 3.2.1.37, 3.2.1.156 (+2 more)	cellulase, endo-1,4-β-xylanase, endo-1,3-β-xylanase, xylan 1,4-β-xylosidase (+1 more)	1,542	1,390
GH11	3.2.1.8, 3.2.1.37	endo-1,4-β-xylanase, xylan 1,4-β-xylosidase	106	99
GH12	3.2.1.4, 3.2.1.73, 3.2.1.151	cellulase, licheninase, xyloglucan-specific endo-β-1,4-glucanase	76	76
GH13_1	3.2.1.1, 3.2.1.116, 2.4.1.25	α-amylase, glucan 1,4-α-maltotriohydrolase, 4-α-glucanotransferase	34	34
GH13_2	3.2.1.1, 3.2.1.116, 3.2.1.133, 2.4.1.19, 2.4.1.-	α-amylase, glucan 1,4-α-maltotriohydrolase, glucan 1,4-α-maltohydrolase, cyclomaltodextrin glucanotransferase	399	383
GH13_3	2.4.99.16	starch synthase (maltosyl-transferring)	742	736
GH13_4	3.2.1.48, 2.4.1.4	sucrose α-glucosidase, amylosucrase	549	547
GH13_5	3.2.1.1, 3.2.1.98, 3.2.1.116, 3.2.1.-	α-amylase, glucan 1,4-α-maltohexaosidase, glucan 1,4-α-maltotriohydrolase	225	224
GH13_6	3.2.1.1, 3.2.1.98	α-amylase, glucan 1,4-α-maltohexaosidase	60	60
GH13_7	3.2.1.1	α-amylase	190	190
GH13_8	3.2.1.1, 2.4.1.18	α-amylase, 1,4-α-glucan branching enzyme	208	208
GH13_9	2.4.1.18	1,4-α-glucan branching enzyme	2,966	2,956
GH13_10	3.2.1.1, 3.2.1.141	α-amylase, 4-α-D-{(1->4)-α-D-glucano}trehalose trehalohydrolase	747	742
GH13_11	3.2.1.20, 3.2.1.68, 2.4.1.25	α-glucosidase, isoamylase, 4-α-glucanotransferase	2,415	2,410
GH13_12	3.2.1.41, 3.2.1.68	pullulanase, isoamylase	23	23
GH13_13	3.2.1.41, 3.2.1.68	pullulanase, isoamylase	552	520
GH13_14	3.2.1.1, 3.2.1.20, 3.2.1.41, 3.2.1.68	α-amylase, α-glucosidase, pullulanase, isoamylase	506	502
GH13_15	3.2.1.1, 2.4.1.25	α-amylase, 4-α-glucanotransferase	30	30
GH13_16	5.4.99.16	maltose α-D-glucosyltransferase	1,079	1,075
GH13_17	3.2.1.20, 3.2.1.48	α-glucosidase, sucrose α-glucosidase	1	1
GH13_18	2.4.1.7, 2.4.1.329, 2.4.1.352, 2.4.1.359, 2.4.1.-	sucrose phosphorylase, sucrose 6(F)-phosphate phosphorylase, glucosylglycerate phosphorylase, glucosylglycerol phosphorylase (configuration-retaining)	1,783	1,782
GH13_19	3.2.1.1, 3.2.1.60, 3.2.1.98, 3.2.1.-	α-amylase, glucan 1,4-α-maltotetraohydrolase, glucan 1,4-α-maltohexaosidase	617	617
GH13_20	3.2.1.1, 3.2.1.41, 3.2.1.54, 3.2.1.68, 3.2.1.133 (+2 more)	α-amylase, pullulanase, cyclomaltodextrinase, isoamylase (+2 more)	1,091	1,077
GH13_21	3.2.1.1, 3.2.1.20, 3.2.1.-	α-amylase, α-glucosidase	220	219
GH13_23	3.2.1.10, 3.2.1.20, 3.2.1.28, 2.4.1.-	oligo-1,6-glucosidase, α-glucosidase, alpha,α-trehalase	2,309	2,227
GH13_24	3.2.1.1	α-amylase	8	8
GH13_26	5.4.99.15	(1->4)-α-D-glucan 1-α-D-glucosylmutase	536	535
GH13_27	3.2.1.1	α-amylase	135	132
GH13_28	3.2.1.1	α-amylase	19	17
GH13_29	3.2.1.20, 3.2.1.93	α-glucosidase, alpha,α-phosphotrehalase	373	373
GH13_30	3.2.1.1, 3.2.1.20, 3.2.1.48, 3.2.1.-	α-amylase, α-glucosidase, sucrose α-glucosidase	578	559
GH13_31	3.2.1.1, 3.2.1.3, 3.2.1.10, 3.2.1.20, 3.2.1.70 (+4 more)	α-amylase, glucan 1,4-α-glucosidase, oligo-1,6-glucosidase, α-glucosidase (+3 more)	1,048	957
GH13_32	3.2.1.1, 3.2.1.116	α-amylase, glucan 1,4-α-maltotriohydrolase	204	201
GH13_33	5.4.99.16	maltose α-D-glucosyltransferase	66	66
GH13_36	3.2.1.1, 3.2.1.54, 3.2.1.133, 3.2.1.135	α-amylase, cyclomaltodextrinase, glucan 1,4-α-maltohydrolase, neopullulanase	313	308
GH13_37	3.2.1.1	α-amylase	57	56
GH13_38	3.2.1.20	α-glucosidase	653	650
GH13_39	3.2.1.1, 3.2.1.41	α-amylase, pullulanase	72	72
GH13_41	3.2.1.1	α-amylase	44	44
GH13_42	3.2.1.1, 3.2.1.98	α-amylase, glucan 1,4-α-maltohexaosidase	41	41
GH13_43	3.2.1.1, 3.2.1.116	α-amylase, glucan 1,4-α-maltotriohydrolase	7	7
GH13_44	3.2.1.20	α-glucosidase	42	42
GH13_45	3.2.1.1, 3.2.1.133	α-amylase, glucan 1,4-α-maltohydrolase	225	225
GH13_46	3.2.1.1, 3.2.1.54, 3.2.1.135	α-amylase, cyclomaltodextrinase, neopullulanase	1,046	1,037
GH13_47	3.2.1.1, 3.2.1.135	α-amylase, neopullulanase	820	819
GH13_48	3.2.1.1, 3.2.1.133	α-amylase, glucan 1,4-α-maltohydrolase	1,296	1,279
GH13_49	3.2.1.1	α-amylase	88	85
GH13	3.2.1.1, 3.2.1.3, 3.2.1.10, 3.2.1.20, 3.2.1.28 (+27 more)	α-amylase, glucan 1,4-α-glucosidase, oligo-1,6-glucosidase, α-glucosidase (+26 more)	25,288	18,575
GH14	3.2.1.2	β-amylase	41	41
GH15	3.2.1.3, 3.2.1.28, 3.2.1.70, 3.2.1.205, 2.4.1.2	glucan 1,4-α-glucosidase, alpha,α-trehalase, glucan 1,6-α-glucosidase, isomaltose glucohydrolase (+1 more)	2,275	2,273
GH16_3	3.2.1.6, 3.2.1.39, 3.2.1.58, 3.2.1.73, 3.2.1.103 (+1 more)	endo-1,3(4)-β-glucanase, glucan endo-1,3-β-D-glucosidase, glucan 1,3-β-glucosidase, licheninase (+1 more)	3,491	3,121
GH16_5	3.2.1.6	endo-1,3(4)-β-glucanase	88	86
GH16_6	—	—	1	1
GH16_7	—	—	27	26
GH16_8	3.2.1.23, 3.2.1.-	β-galactosidase	1	1
GH16_9	—	—	11	11
GH16_10	3.2.1.181	galactan endo-β-1,3-galactanase	6	6
GH16_11	3.2.1.178	β-porphyranase	76	62
GH16_12	3.2.1.178	β-porphyranase	31	29
GH16_13	3.2.1.83, 3.2.1.-	kappa-carrageenase	91	72
GH16_14	3.2.1.81, 3.2.1.178	β-agarase, β-porphyranase	31	30
GH16_15	3.2.1.81	β-agarase	37	37
GH16_16	3.2.1.81, 3.2.1.178	β-agarase, β-porphyranase	104	97
GH16_17	3.2.1.83, 3.2.1.-	kappa-carrageenase	48	44
GH16_21	3.2.1.6, 3.2.1.21, 3.2.1.73	endo-1,3(4)-β-glucanase, β-glucosidase, licheninase	157	152
GH16_24	3.2.1.-	—	15	15
GH16_25	3.2.1.21, 3.2.1.73	β-glucosidase, licheninase	43	40
GH16_26	3.2.1.178	β-porphyranase	12	12
GH16	3.2.1.6, 3.2.1.21, 3.2.1.23, 3.2.1.35, 3.2.1.39 (+11 more)	endo-1,3(4)-β-glucanase, β-glucosidase, β-galactosidase, hyaluronoglucosaminidase (+10 more)	4,502	4,003
GH17	3.2.1.39, 3.2.1.58, 3.2.1.73, 3.2.1.175, 2.4.1.-	glucan endo-1,3-β-D-glucosidase, glucan 1,3-β-glucosidase, licheninase, β-D-glucopyranosyl abscisate β-glucosidase	1,614	959
GH18	3.2.1.14, 3.2.1.52, 3.2.1.96, 3.2.1.132, 3.2.1.200 (+2 more)	chitinase, β-N-acetylhexosaminidase, mannosyl-glycoprotein endo-β-N-acetylglucosaminidase, chitosanase (+2 more)	2,342	2,130
GH19_1	3.2.1.17	lysozyme	117	117
GH19_2	3.2.1.14, 3.2.1.201	chitinase, exo-chitinase (reducing end)	65	65
GH19	3.2.1.14, 3.2.1.17, 3.2.1.201	chitinase, lysozyme, exo-chitinase (reducing end)	427	422
GH20	3.2.1.52, 3.2.1.53, 3.2.1.96, 3.2.1.140, 3.2.1.-	β-N-acetylhexosaminidase, β-N-acetylgalactosaminidase, mannosyl-glycoprotein endo-β-N-acetylglucosaminidase, lacto-N-biosidase	3,755	3,628
GH23	3.2.1.14, 3.2.1.17, 4.2.2.29	chitinase, lysozyme, peptidoglycan lytic transglycosylase	12,700	12,462
GH24	3.2.1.17	lysozyme	310	309
GH25	3.2.1.17	lysozyme	701	696
GH26	3.2.1.4, 3.2.1.32, 3.2.1.73, 3.2.1.78, 3.2.1.100 (+2 more)	cellulase, endo-1,3-β-xylanase, licheninase, mannan endo-1,4-β-mannosidase (+2 more)	839	730
GH27	3.2.1.11, 3.2.1.22, 3.2.1.49, 3.2.1.88, 3.2.1.94 (+2 more)	dextranase, α-galactosidase, α-N-acetylgalactosaminidase, non-reducing end β-L-arabinopyranosidase (+1 more)	505	492
GH28	3.2.1.15, 3.2.1.67, 3.2.1.82, 3.2.1.171, 3.2.1.173 (+1 more)	endo-polygalacturonase, galacturonan 1,4-α-galacturonidase, exo-poly-α-digalacturonosidase, rhamnogalacturonan hydrolase (+1 more)	975	870
GH29	3.2.1.51, 3.2.1.63, 3.2.1.111, 3.2.1.127, 3.2.1.-	α-L-fucosidase, 1,2-α-L-fucosidase, 1,3-α-L-fucosidase, 1,6-α-L-fucosidase	2,524	2,155
GH30_1	3.2.1.21, 3.2.1.45, 3.2.1.-	β-glucosidase, glucosylceramidase	1,060	1,048
GH30_2	3.2.1.37, 3.2.1.-	xylan 1,4-β-xylosidase	79	78
GH30_3	3.2.1.75, 3.2.1.-	glucan endo-1,6-β-glucosidase	340	291
GH30_4	3.2.1.38	β-D-fucosidase	168	145
GH30_5	3.2.1.164, 3.2.1.213, 3.2.1.-	galactan endo-1,6-β-galactosidase, galactan exo-1,6-β-galactobiohydrolase (non-reducing end)	54	52
GH30_7	3.2.1.8, 3.2.1.37, 3.2.1.156, 3.2.1.-	endo-1,4-β-xylanase, xylan 1,4-β-xylosidase, oligosaccharide reducing-end xylanase	3	3
GH30_8	3.2.1.8, 3.2.1.136, 3.2.1.-	endo-1,4-β-xylanase, glucuronoarabinoxylan endo-1,4-β-xylanase	57	56
GH30_10	3.2.1.-	—	5	5
GH30_11	3.2.1.38, 3.2.1.-	β-D-fucosidase	4	4
GH30_12	3.2.1.8, 3.2.1.136	endo-1,4-β-xylanase, glucuronoarabinoxylan endo-1,4-β-xylanase	7	7
GH30	3.2.1.8, 3.2.1.21, 3.2.1.37, 3.2.1.38, 3.2.1.45 (+7 more)	endo-1,4-β-xylanase, β-glucosidase, xylan 1,4-β-xylosidase, β-D-fucosidase (+7 more)	1,875	1,686
GH31_1	3.2.1.10, 3.2.1.20, 3.2.1.24, 3.2.1.48, 3.2.1.84 (+2 more)	oligo-1,6-glucosidase, α-glucosidase, α-mannosidase, sucrose α-glucosidase (+3 more)	653	651
GH31_2	—	—	180	176
GH31_3	3.2.1.20, 3.2.1.177	α-glucosidase, α-D-xyloside xylohydrolase	419	419
GH31_4	3.2.1.177	α-D-xyloside xylohydrolase	268	259
GH31_6	—	—	23	23
GH31_7	3.2.1.204, 2.4.1.387	1,3-α-isomaltosidase, isomaltosyltransferase	72	68
GH31_8	4.2.2.13	exo-(1->4)-α-D-glucan lyase	4	4
GH31_9	—	—	18	18
GH31_10	2.4.1.24	1,4-α-glucan 6-α-glucosyltransferase	8	8
GH31_12	2.4.1.24	1,4-α-glucan 6-α-glucosyltransferase	28	28
GH31_13	3.2.1.199	sulfoquinovosidase	211	211
GH31_14	3.2.1.22	α-galactosidase	62	62
GH31_15	3.2.1.20, 3.2.1.84	α-glucosidase, glucan 1,3-α-glucosidase	77	76
GH31_16	—	—	5	5
GH31_17	—	—	6	6
GH31_18	3.2.1.217	exo-acting protein-α-N-acetylgalactosaminidase	51	51
GH31_19	3.2.1.22, 3.2.1.-	α-galactosidase	70	70
GH31_20	3.2.1.22	α-galactosidase	11	11
GH31	3.2.1.10, 3.2.1.11, 3.2.1.20, 3.2.1.22, 3.2.1.24 (+12 more)	oligo-1,6-glucosidase, dextranase, α-glucosidase, α-galactosidase (+12 more)	2,699	2,644
GH32	3.2.1.7, 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.153 (+7 more)	inulinase, β-fructofuranosidase, 2,6-β-fructan 6-levanbiohydrolase, levanase (+6 more)	2,013	1,804
GH33	3.2.1.18, 3.2.1.124, 3.2.1.-, 2.4.1.-, 4.2.2.15	exo-α-sialidase, 3-deoxy-2-octulosonidase, anhydrosialidase	2,081	1,972
GH35	3.2.1.23, 3.2.1.165, 3.2.1.-, 2.4.1.391	β-galactosidase, exo-1,4-β-D-glucosaminidase, β-1,2-glucosyltransferase	492	472
GH36	3.2.1.22, 3.2.1.49, 3.2.1.88, 3.2.1.-, 2.4.1.67 (+1 more)	α-galactosidase, α-N-acetylgalactosaminidase, non-reducing end β-L-arabinopyranosidase, galactinol--raffinose galactosyltransferase (+1 more)	1,517	1,497
GH37	3.2.1.28	alpha,α-trehalase	643	642
GH38	3.2.1.24, 3.2.1.113, 3.2.1.114, 3.2.1.163, 3.2.1.-	α-mannosidase, mannosyl-oligosaccharide 1,2-α-mannosidase, mannosyl-oligosaccharide 1,3-1,6-α-mannosidase, 1,6-α-D-mannosidase	1,269	1,217
GH39	3.2.1.21, 3.2.1.23, 3.2.1.37, 3.2.1.74, 3.2.1.76 (+3 more)	β-glucosidase, β-galactosidase, xylan 1,4-β-xylosidase, glucan 1,4-β-glucosidase (+3 more)	779	732
GH42	3.2.1.23, 3.2.1.-	β-galactosidase	1,246	1,232
GH43_1	3.2.1.37, 3.2.1.55, 3.2.1.-	xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase	454	452
GH43_2	3.2.1.37, 3.2.1.55	xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase	130	123
GH43_3	3.2.1.146	β-galactofuranosidase	103	95
GH43_4	3.2.1.99, 3.2.1.-	arabinan endo-1,5-α-L-arabinosidase	214	194
GH43_5	3.2.1.99, 3.2.1.-	arabinan endo-1,5-α-L-arabinosidase	348	332
GH43_7	3.2.1.8, 3.2.1.-	endo-1,4-β-xylanase	16	16
GH43_8	3.2.1.146	β-galactofuranosidase	40	40
GH43_9	3.2.1.55	non-reducing end α-L-arabinofuranosidase	128	127
GH43_10	3.2.1.37, 3.2.1.55, 3.2.1.-	xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase	339	337
GH43_11	3.2.1.37, 3.2.1.55, 3.2.1.72	xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase, xylan 1,3-β-xylosidase	497	495
GH43_12	3.2.1.37, 3.2.1.55, 3.2.1.72, 3.2.1.-	xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase, xylan 1,3-β-xylosidase	459	451
GH43_15	—	—	7	5
GH43_16	3.2.1.8, 3.2.1.37, 3.2.1.55	endo-1,4-β-xylanase, xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase	37	37
GH43_17	3.2.1.8, 3.2.1.55	endo-1,4-β-xylanase, non-reducing end α-L-arabinofuranosidase	92	91
GH43_18	3.2.1.55	non-reducing end α-L-arabinofuranosidase	220	219
GH43_19	3.2.1.55	non-reducing end α-L-arabinofuranosidase	105	88
GH43_20	3.2.1.55	non-reducing end α-L-arabinofuranosidase	10	10
GH43_21	3.2.1.55	non-reducing end α-L-arabinofuranosidase	1	1
GH43_22	3.2.1.37, 3.2.1.55, 3.2.1.99, 3.2.1.-	xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase, arabinan endo-1,5-α-L-arabinosidase	75	67
GH43_23	3.2.1.55	non-reducing end α-L-arabinofuranosidase	24	24
GH43_24	3.2.1.145, 3.2.1.181	galactan 1,3-β-galactosidase, galactan endo-β-1,3-galactanase	163	157
GH43_26	3.2.1.55, 3.2.1.-	non-reducing end α-L-arabinofuranosidase	590	517
GH43_27	3.2.1.37, 3.2.1.55, 3.2.1.-	xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase	10	8
GH43_28	—	—	216	211
GH43_29	3.2.1.37, 3.2.1.55, 3.2.1.-	xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase	306	275
GH43_30	3.2.1.146	β-galactofuranosidase	52	51
GH43_31	3.2.1.146	β-galactofuranosidase	68	62
GH43_32	3.2.1.146	β-galactofuranosidase	42	41
GH43_33	3.2.1.55	non-reducing end α-L-arabinofuranosidase	60	60
GH43_34	3.2.1.55, 3.2.1.146	non-reducing end α-L-arabinofuranosidase, β-galactofuranosidase	233	231
GH43_35	3.2.1.8, 3.2.1.37, 3.2.1.55	endo-1,4-β-xylanase, xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase	26	25
GH43_36	3.2.1.8, 3.2.1.55	endo-1,4-β-xylanase, non-reducing end α-L-arabinofuranosidase	19	19
GH43_37	3.2.1.99, 3.2.1.146	arabinan endo-1,5-α-L-arabinosidase, β-galactofuranosidase	37	36
GH43	3.2.1.8, 3.2.1.37, 3.2.1.55, 3.2.1.72, 3.2.1.99 (+4 more)	endo-1,4-β-xylanase, xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase, xylan 1,3-β-xylosidase (+4 more)	5,183	4,059
GH44	3.2.1.4, 3.2.1.8, 3.2.1.73, 3.2.1.151	cellulase, endo-1,4-β-xylanase, licheninase, xyloglucan-specific endo-β-1,4-glucanase	47	47
GH45_1	3.2.1.4, 3.2.1.151, 3.2.1.-	cellulase, xyloglucan-specific endo-β-1,4-glucanase	2	2
GH45	3.2.1.4, 3.2.1.151, 3.2.1.-	cellulase, xyloglucan-specific endo-β-1,4-glucanase	5	5
GH46	3.2.1.132	chitosanase	94	86
GH47	3.2.1.113	mannosyl-oligosaccharide 1,2-α-mannosidase	50	49
GH48	3.2.1.4, 3.2.1.14, 3.2.1.91, 3.2.1.176	cellulase, chitinase, cellulose 1,4-β-cellobiosidase (non-reducing end), cellulose 1,4-β-cellobiosidase (reducing end)	55	53
GH49	3.2.1.11, 3.2.1.57, 3.2.1.95, 3.2.1.-	dextranase, isopullulanase, dextran 1,6-α-isomaltotriosidase	28	27
GH50	3.2.1.23, 3.2.1.39, 3.2.1.81	β-galactosidase, glucan endo-1,3-β-D-glucosidase, β-agarase	387	341
GH51_1	3.2.1.55, 3.2.1.91, 3.2.1.-	non-reducing end α-L-arabinofuranosidase, cellulose 1,4-β-cellobiosidase (non-reducing end)	1,015	953
GH51_2	3.2.1.37, 3.2.1.55	xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase	155	153
GH51_3	3.2.1.4, 3.2.1.8	cellulase, endo-1,4-β-xylanase	77	74
GH51_4	—	—	15	15
GH51_5	—	—	12	12
GH51_6	—	—	12	11
GH51_9	—	—	6	6
GH51_11	—	—	4	3
GH51_12	—	—	9	9
GH51_13	—	—	16	16
GH51_14	—	—	5	5
GH51	3.2.1.4, 3.2.1.6, 3.2.1.8, 3.2.1.37, 3.2.1.55 (+2 more)	cellulase, endo-1,3(4)-β-glucanase, endo-1,4-β-xylanase, xylan 1,4-β-xylosidase (+2 more)	1,337	1,218
GH52	3.2.1.37	xylan 1,4-β-xylosidase	65	65
GH53	3.2.1.89, 3.2.1.-	arabinogalactan endo-β-1,4-galactanase	505	455
GH54	3.2.1.23, 3.2.1.37, 3.2.1.55	β-galactosidase, xylan 1,4-β-xylosidase, non-reducing end α-L-arabinofuranosidase	24	21
GH55_1	3.2.1.39, 3.2.1.58, 3.2.1.168	glucan endo-1,3-β-D-glucosidase, glucan 1,3-β-glucosidase, hesperidin 6-O-α-L-rhamnosyl-β-D-glucosidase	113	113
GH55_2	3.2.1.39, 3.2.1.58, 3.2.1.-	glucan endo-1,3-β-D-glucosidase, glucan 1,3-β-glucosidase	3	3
GH55_3	—	—	39	33
GH55	3.2.1.39, 3.2.1.58, 3.2.1.168, 3.2.1.-	glucan endo-1,3-β-D-glucosidase, glucan 1,3-β-glucosidase, hesperidin 6-O-α-L-rhamnosyl-β-D-glucosidase	175	169
GH57_1	3.2.1.1, 2.4.1.25	α-amylase, 4-α-glucanotransferase	430	430
GH57_2	3.2.1.1, 3.2.1.41	α-amylase, pullulanase	515	515
GH57_3	3.2.1.1, 2.4.1.18	α-amylase, 1,4-α-glucan branching enzyme	320	311
GH57_4	3.2.1.22	α-galactosidase	14	14
GH57_5	3.2.1.1, 2.4.1.18	α-amylase, 1,4-α-glucan branching enzyme	647	646
GH57_6	3.2.1.1, 2.4.1.25	α-amylase, 4-α-glucanotransferase	300	300
GH57_7	3.2.1.1, 3.2.1.41, 3.2.1.54	α-amylase, pullulanase, cyclomaltodextrinase	12	12
GH57_8	3.2.1.133	glucan 1,4-α-maltohydrolase	26	26
GH57_9	—	—	68	58
GH57_10	—	—	42	42
GH57	3.2.1.1, 3.2.1.22, 3.2.1.41, 3.2.1.54, 3.2.1.133 (+2 more)	α-amylase, α-galactosidase, pullulanase, cyclomaltodextrinase (+3 more)	2,473	2,331
GH59	3.2.1.46	galactosylceramidase	36	35
GH62	3.2.1.8, 3.2.1.55, 3.2.1.-	endo-1,4-β-xylanase, non-reducing end α-L-arabinofuranosidase	73	72
GH63	3.2.1.20, 3.2.1.84, 3.2.1.106, 3.2.1.170, 3.2.1.208	α-glucosidase, glucan 1,3-α-glucosidase, mannosyl-oligosaccharide glucosidase, mannosylglycerate hydrolase (+1 more)	1,602	1,595
GH64	3.2.1.39	glucan endo-1,3-β-D-glucosidase	108	107
GH65	3.2.1.28, 3.2.1.107, 3.2.1.216, 3.2.1.115, 2.4.1.8 (+8 more)	alpha,α-trehalase, protein-glucosylgalactosylhydroxylysine glucosidase, kojibiose hydrolase, branched-dextran exo-1,2-α-glucosidase (+8 more)	2,000	1,969
GH66	3.2.1.11, 2.4.1.248	dextranase, cycloisomaltooligosaccharide glucanotransferase	75	65
GH67	3.2.1.131	xylan α-1,2-glucuronosidase	330	328
GH68_1	2.4.1.9, 2.4.1.10	inulosucrase, levansucrase	23	22
GH68_2	3.2.1.26, 2.4.1.9, 2.4.1.10	β-fructofuranosidase, inulosucrase, levansucrase	95	91
GH68	3.2.1.26, 2.4.1.9, 2.4.1.10	β-fructofuranosidase, inulosucrase, levansucrase	134	129
GH70	2.4.1.5, 2.4.1.140, 2.4.1.-	dextransucrase, alternansucrase	1	1
GH71	3.2.1.59, 3.2.1.84, 3.2.1.-	glucan endo-1,3-α-glucosidase, glucan 1,3-α-glucosidase	16	15
GH73	3.2.1.96, 3.2.1.-	mannosyl-glycoprotein endo-β-N-acetylglucosaminidase	2,229	2,215
GH74	3.2.1.4, 3.2.1.150, 3.2.1.151	cellulase, oligoxyloglucan reducing-end-specific cellobiohydrolase, xyloglucan-specific endo-β-1,4-glucanase	209	208
GH75	3.2.1.132	chitosanase	8	8
GH76	3.2.1.20, 3.2.1.101	α-glucosidase, mannan endo-1,6-α-mannosidase	267	241
GH77	2.4.1.25	4-α-glucanotransferase	2,365	2,359
GH78	3.2.1.40, 3.2.1.174, 3.2.1.-	α-L-rhamnosidase, rhamnogalacturonan rhamnohydrolase	1,515	1,327
GH79	3.2.1.31, 3.2.1.36, 3.2.1.128, 3.2.1.166, 3.2.1.167 (+1 more)	β-glucuronidase, hyaluronoglucuronidase, glycyrrhizinate β-glucuronidase, heparanase (+1 more)	71	71
GH81	3.2.1.39	glucan endo-1,3-β-D-glucosidase	343	342
GH82	3.2.1.157	iota-carrageenase	42	36
GH84	3.2.1.35, 3.2.1.52, 3.2.1.169	hyaluronoglucosaminidase, β-N-acetylhexosaminidase, protein O-GlcNAcase	323	322
GH85	3.2.1.96	mannosyl-glycoprotein endo-β-N-acetylglucosaminidase	78	78
GH86	3.2.1.81, 3.2.1.178, 3.2.1.222	β-agarase, β-porphyranase, funoran endo-β-hydrolase	162	145
GH87	3.2.1.59, 3.2.1.61	glucan endo-1,3-α-glucosidase, mycodextranase	118	101
GH88	3.2.1.179, 3.2.1.180, 3.2.1.-	gellan tetrasaccharide unsaturated glucuronosyl hydrolase, unsaturated chondroitin disaccharide hydrolase	863	859
GH89	3.2.1.50	α-N-acetylglucosaminidase	114	112
GH91	3.2.1.-	—	19	17
GH92	3.2.1.24, 3.2.1.113, 3.2.1.-	α-mannosidase, mannosyl-oligosaccharide 1,2-α-mannosidase	2,865	2,185
GH93	3.2.1.-	—	78	75
GH94	2.4.1.20, 2.4.1.31, 2.4.1.49, 2.4.1.280, 2.4.1.321 (+4 more)	cellobiose phosphorylase, laminaribiose phosphorylase, cellodextrin phosphorylase, N,N'-diacetylchitobiose phosphorylase (+4 more)	907	866
GH95	3.2.1.51, 3.2.1.63, 3.2.1.-	α-L-fucosidase, 1,2-α-L-fucosidase	1,059	1,013
GH96	3.2.1.158, 3.2.1.228	α-agarase, funoran endo-α-hydrolase	18	17
GH97	3.2.1.3, 3.2.1.20, 3.2.1.22, 3.2.1.70, 3.2.1.88	glucan 1,4-α-glucosidase, α-glucosidase, α-galactosidase, glucan 1,6-α-glucosidase (+1 more)	1,412	1,379
GH98	3.2.1.8, 3.2.1.102	endo-1,4-β-xylanase, blood-group-substance endo-1,4-β-galactosidase	6	6
GH99	3.2.1.130, 3.2.1.198	glycoprotein endo-α-1,2-mannosidase, α-mannan endo-1,2-α-mannanase	204	198
GH100	3.2.1.26	β-fructofuranosidase	551	546
GH101	3.2.1.97	endo-α-N-acetylgalactosaminidase	44	43
GH102	4.2.2.29	peptidoglycan lytic transglycosylase	1,219	1,219
GH103	4.2.2.29	peptidoglycan lytic transglycosylase	5,980	5,964
GH104	4.2.2.29	peptidoglycan lytic transglycosylase	77	77
GH105	3.2.1.172, 3.2.1.-	unsaturated rhamnogalacturonyl hydrolase	1,165	1,096
GH106	3.2.1.40, 3.2.1.174, 3.2.1.-	α-L-rhamnosidase, rhamnogalacturonan rhamnohydrolase	708	634
GH107	3.2.1.211, 3.2.1.212	endo-(1->3)-fucoidanase, endo-(1->4)-fucoidanase	13	8
GH108	3.2.1.17	lysozyme	656	656
GH109	3.2.1.35, 3.2.1.49, 3.2.1.52, 3.2.1.217	hyaluronoglucosaminidase, α-N-acetylgalactosaminidase, β-N-acetylhexosaminidase, exo-acting protein-α-N-acetylgalactosaminidase	1,131	1,124
GH110	3.2.1.22, 3.2.1.-	α-galactosidase	160	134
GH111	3.2.1.-	—	1	1
GH112	2.4.1.211, 2.4.1.247, 2.4.1.-	1,3-β-galactosyl-N-acetylhexosamine phosphorylase, β-D-galactosyl-(1->4)-L-rhamnose phosphorylase	32	32
GH113	3.2.1.25, 3.2.1.78, 3.2.1.-	β-mannosidase, mannan endo-1,4-β-mannosidase	557	554
GH114	3.2.1.109	endogalactosaminidase	261	259
GH115	3.2.1.131, 3.2.1.-	xylan α-1,2-glucuronosidase	317	313
GH116	3.2.1.21, 3.2.1.37, 3.2.1.45, 3.2.1.52, 3.2.1.-	β-glucosidase, xylan 1,4-β-xylosidase, glucosylceramidase, β-N-acetylhexosaminidase	344	337
GH117	3.2.1.146, 3.2.1.159, 3.2.1.-	β-galactofuranosidase, α-neoagaro-oligosaccharide hydrolase	586	477
GH119	3.2.1.1	α-amylase	19	19
GH120	3.2.1.37	xylan 1,4-β-xylosidase	81	78
GH121	3.2.1.187	(Ara-f)3-Hyp β-L-arabinobiosidase	14	13
GH122	3.2.1.20	α-glucosidase	29	29
GH123_1	3.2.1.53, 3.2.1.-	β-N-acetylgalactosaminidase	49	45
GH123_2	3.2.1.53, 3.2.1.-	β-N-acetylgalactosaminidase	29	29
GH123_3	3.2.1.53, 3.2.1.-	β-N-acetylgalactosaminidase	65	63
GH123_4	3.2.1.53	β-N-acetylgalactosaminidase	20	20
GH123	3.2.1.53, 3.2.1.-	β-N-acetylgalactosaminidase	175	168
GH125	3.2.1.163	1,6-α-D-mannosidase	298	298
GH126	3.2.1.1	α-amylase	62	62
GH127	3.2.1.185, 3.2.1.-	non-reducing end β-L-arabinofuranosidase	897	844
GH128	3.2.1.39, 3.2.1.58	glucan endo-1,3-β-D-glucosidase, glucan 1,3-β-glucosidase	156	151
GH129	3.2.1.49, 3.2.1.-	α-N-acetylgalactosaminidase	101	100
GH130_1	2.4.1.281	4-O-β-D-mannosyl-D-glucose phosphorylase	324	324
GH130_2	2.4.1.319, 2.4.1.320	β-1,4-mannooligosaccharide phosphorylase, 1,4-β-mannosyl-N-acetylglucosamine phosphorylase	259	259
GH130_3	3.2.1.197	β-1,2-mannosidase	211	211
GH130_4	2.4.1.339, 2.4.1.340	β-1,2-mannobiose phosphorylase, 1,2-β-oligomannan phosphorylase	192	192
GH130_5	2.4.1.-	—	69	69
GH130_6	2.4.1.339, 2.4.1.340	β-1,2-mannobiose phosphorylase, 1,2-β-oligomannan phosphorylase	138	125
GH130_7	2.4.1.281	4-O-β-D-mannosyl-D-glucose phosphorylase	17	17
GH130_8	—	—	287	287
GH130_9	—	—	288	280
GH130_10	—	—	7	7
GH130_11	2.4.1.-	—	47	47
GH130_12	—	—	24	24
GH130_13	2.4.1.-	—	1	1
GH130_14	—	—	58	58
GH130_15	—	—	43	43
GH130_16	—	—	43	43
GH130	3.2.1.197, 2.4.1.281, 2.4.1.319, 2.4.1.320, 2.4.1.339 (+2 more)	β-1,2-mannosidase, 4-O-β-D-mannosyl-D-glucose phosphorylase, β-1,4-mannooligosaccharide phosphorylase, 1,4-β-mannosyl-N-acetylglucosamine phosphorylase (+2 more)	2,096	1,919
GH133	3.2.1.33	amylo-α-1,6-glucosidase	536	536
GH134	3.2.1.78	mannan endo-1,4-β-mannosidase	2	2
GH135	3.2.1.-	—	52	51
GH136	3.2.1.140, 3.2.1.-	lacto-N-biosidase	311	274
GH137	3.2.1.185	non-reducing end β-L-arabinofuranosidase	65	64
GH138	3.2.1.173	rhamnogalacturonan galacturonohydrolase	60	60
GH139	3.2.1.-	—	87	83
GH140	3.2.1.-	—	321	314
GH141	3.2.1.8, 3.2.1.51	endo-1,4-β-xylanase, α-L-fucosidase	551	517
GH142	3.2.1.185	non-reducing end β-L-arabinofuranosidase	122	122
GH143	3.2.1.-	—	46	46
GH144	3.2.1.71, 3.2.1.214	glucan endo-1,2-β-glucosidase, exo β-1,2-glucooligosaccharide sophorohydrolase (non-reducing end)	995	746
GH146	3.2.1.185	non-reducing end β-L-arabinofuranosidase	391	384
GH147	3.2.1.23, 3.2.1.89	β-galactosidase, arabinogalactan endo-β-1,4-galactanase	98	97
GH148	3.2.1.4, 3.2.1.73, 3.2.1.-	cellulase, licheninase	153	152
GH149	2.4.1.97	1,3-β-D-glucan phosphorylase	1,004	1,000
GH150	3.2.1.162	lambda-carrageenase	33	27
GH151	3.2.1.51	α-L-fucosidase	238	231
GH152	3.2.1.39	glucan endo-1,3-β-D-glucosidase	4	4
GH153	3.2.1.-	—	7	7
GH154	3.2.1.-	—	352	346
GH156	3.2.1.18	exo-α-sialidase	181	173
GH157	3.2.1.6, 3.2.1.39	endo-1,3(4)-β-glucanase, glucan endo-1,3-β-D-glucosidase	23	23
GH158	3.2.1.39	glucan endo-1,3-β-D-glucosidase	546	534
GH159	3.2.1.55, 3.2.1.146	non-reducing end α-L-arabinofuranosidase, β-galactofuranosidase	79	79
GH161	2.4.1.97	1,3-β-D-glucan phosphorylase	112	111
GH163	3.2.1.-	—	325	323
GH164	3.2.1.25	β-mannosidase	17	17
GH165	3.2.1.23	β-galactosidase	740	691
GH166	3.2.1.-	—	262	262
GH167	3.2.1.-	—	61	56
GH168	3.2.1.211, 3.2.1.212, 3.2.1.-	endo-(1->3)-fucoidanase, endo-(1->4)-fucoidanase	72	59
GH170	3.2.1.-	—	220	208
GH171	3.2.1.92	peptidoglycan β-N-acetylmuramidase	2,609	2,563
GH172	3.2.1.-	—	632	597
GH173	3.2.1.23	β-galactosidase	56	38
GH174	3.2.1.211, 3.2.1.-	endo-(1->3)-fucoidanase	15	15
GH175	3.2.1.21	β-glucosidase	52	51
GH176	3.2.1.68	isoamylase	447	440
GH177	3.2.1.18	exo-α-sialidase	1,765	1,686
GH178	3.2.1.-	—	461	461
GH179	3.2.1.52	β-N-acetylhexosaminidase	368	368
GH180	—	—	5	5
GH181	3.2.1.18	exo-α-sialidase	19	19
GH182	3.2.1.146	β-galactofuranosidase	49	49
GH183	3.2.1.-	—	139	129
GH184	3.2.1.17	lysozyme	190	178
GH185	3.2.1.-	—	6	6
GH186	3.2.1.71	glucan endo-1,2-β-glucosidase	1,574	1,512
GH187	3.2.1.-, 3.2.1.211	endo-(1->3)-fucoidanase	36	36
GH188	3.2.1.199	sulfoquinovosidase	1,101	1,101
GH189	2.4.1.391, 2.4.1.397	β-1,2-glucosyltransferase, cyclic β-1,2-glucan glucanotransferase	305	305
GH190	4.2.2.29	peptidoglycan lytic transglycosylase	28	27
GH191	3.2.1.-	—	209	208
GH192	3.2.1.71	glucan endo-1,2-β-glucosidase	68	67
GH193	3.2.1.71	glucan endo-1,2-β-glucosidase	8	6
GH194	3.2.1.71	glucan endo-1,2-β-glucosidase	18	18

PL Polysaccharide Lyases · 98 families and subfamilies · 8,301 genes · 6,211 CGCs

Family	EC numbers	Activity (EC name)	Genes	CGCs
PL1_2	4.2.2.2	pectate lyase	634	541
PL1_3	4.2.2.2	pectate lyase	3	3
PL1_4	4.2.2.10	pectin lyase	2	2
PL1_5	4.2.2.2, 4.2.2.10	pectate lyase, pectin lyase	98	92
PL1_6	4.2.2.2	pectate lyase	83	76
PL1_7	4.2.2.2	pectate lyase	3	3
PL1_8	4.2.2.10	pectin lyase	7	7
PL1_9	—	—	5	5
PL1_11	—	—	7	7
PL1_12	—	—	1	1
PL1_13	4.2.2.-	—	3	3
PL1	4.2.2.2, 4.2.2.10, 4.2.2.-	pectate lyase, pectin lyase	979	820
PL2_1	4.2.2.2, 4.2.2.9	pectate lyase, pectate disaccharide-lyase	12	12
PL2_2	4.2.2.9	pectate disaccharide-lyase	18	18
PL2	4.2.2.2, 4.2.2.9	pectate lyase, pectate disaccharide-lyase	41	41
PL3_1	4.2.2.2	pectate lyase	19	19
PL3_4	4.2.2.2	pectate lyase	24	24
PL3_5	4.2.2.2	pectate lyase	9	9
PL3	4.2.2.2	pectate lyase	53	53
PL4_1	4.2.2.23	rhamnogalacturonan endolyase	16	16
PL4_2	—	—	1	1
PL4	4.2.2.23	rhamnogalacturonan endolyase	29	28
PL5_1	4.2.2.3	mannuronate-specific alginate lyase	62	62
PL5	4.2.2.3, 4.2.2.14	mannuronate-specific alginate lyase, glucuronan lyase	135	133
PL6_1	4.2.2.3, 4.2.2.11, 4.2.2.26, 4.2.2.-	mannuronate-specific alginate lyase, guluronate-specific alginate lyase, oligo-alginate lyase	54	53
PL6_2	4.2.2.3, 4.2.2.11, 4.2.2.-	mannuronate-specific alginate lyase, guluronate-specific alginate lyase	40	38
PL6_3	—	—	36	36
PL6	4.2.2.3, 4.2.2.11, 4.2.2.19, 4.2.2.26, 4.2.2.-	mannuronate-specific alginate lyase, guluronate-specific alginate lyase, chondroitin B lyase, oligo-alginate lyase	826	739
PL7_1	4.2.2.-	—	55	53
PL7_2	—	—	6	6
PL7_3	4.2.2.3, 4.2.2.11, 4.2.2.-	mannuronate-specific alginate lyase, guluronate-specific alginate lyase	75	66
PL7_4	4.2.2.14	glucuronan lyase	2	2
PL7_5	4.2.2.3, 4.2.2.11, 4.2.2.26, 4.2.2.-	mannuronate-specific alginate lyase, guluronate-specific alginate lyase, oligo-alginate lyase	561	478
PL7	4.2.2.3, 4.2.2.11, 4.2.2.14, 4.2.2.26, 4.2.2.-	mannuronate-specific alginate lyase, guluronate-specific alginate lyase, glucuronan lyase, oligo-alginate lyase	1,024	793
PL8_1	4.2.2.1	hyaluronate lyase	7	7
PL8_2	4.2.2.5, 4.2.2.7, 4.2.2.19	chondroitin AC lyase, heparin lyase, chondroitin B lyase	73	58
PL8_3	4.2.2.5	chondroitin AC lyase	107	100
PL8	4.2.2.1, 4.2.2.3, 4.2.2.5, 4.2.2.7, 4.2.2.12 (+2 more)	hyaluronate lyase, mannuronate-specific alginate lyase, chondroitin AC lyase, heparin lyase (+2 more)	276	242
PL9_1	4.2.2.2, 4.2.2.9, 4.2.2.10, 4.2.2.23	pectate lyase, pectate disaccharide-lyase, pectin lyase, rhamnogalacturonan endolyase	101	99
PL9_2	—	—	141	136
PL9_3	4.2.2.2	pectate lyase	19	18
PL9_4	4.2.2.-	—	53	53
PL9	4.2.2.2, 4.2.2.9, 4.2.2.10, 4.2.2.23, 4.2.2.-	pectate lyase, pectate disaccharide-lyase, pectin lyase, rhamnogalacturonan endolyase	460	451
PL10_1	4.2.2.2	pectate lyase	200	196
PL10_2	—	—	24	24
PL10_3	—	—	126	126
PL10	4.2.2.2	pectate lyase	356	350
PL11_1	4.2.2.23, 4.2.2.24	rhamnogalacturonan endolyase, rhamnogalacturonan exolyase	112	107
PL11_2	—	—	12	12
PL11	4.2.2.23, 4.2.2.24	rhamnogalacturonan endolyase, rhamnogalacturonan exolyase	317	295
PL12_1	—	—	23	23
PL12_2	4.2.2.7, 4.2.2.8	heparin lyase, heparin-sulfate lyase	22	22
PL12_3	—	—	231	229
PL12	4.2.2.7, 4.2.2.8	heparin lyase, heparin-sulfate lyase	832	825
PL13	4.2.2.7, 4.2.2.-	heparin lyase	2	2
PL14_3	4.2.2.3	mannuronate-specific alginate lyase	47	46
PL14	4.2.2.3, 4.2.2.14, 4.2.2.-	mannuronate-specific alginate lyase, glucuronan lyase	130	118
PL15_1	4.2.2.26, 4.2.2.-	oligo-alginate lyase	123	123
PL15_2	4.2.2.-	—	14	12
PL15	4.2.2.3, 4.2.2.-, 4.2.2.26	mannuronate-specific alginate lyase, oligo-alginate lyase	221	219
PL17_1	4.2.2.26	oligo-alginate lyase	32	30
PL17_2	4.2.2.3, 4.2.2.26, 4.2.2.-	mannuronate-specific alginate lyase, oligo-alginate lyase	615	564
PL17_3	4.2.2.1	hyaluronate lyase	40	40
PL17_4	—	—	2	2
PL17_5	4.2.2.11	guluronate-specific alginate lyase	3	3
PL17_6	—	—	16	16
PL17	4.2.2.1, 4.2.2.3, 4.2.2.11, 4.2.2.26, 4.2.2.-	hyaluronate lyase, mannuronate-specific alginate lyase, guluronate-specific alginate lyase, oligo-alginate lyase	725	666
PL18	4.2.2.3, 4.2.2.11, 4.2.2.-	mannuronate-specific alginate lyase, guluronate-specific alginate lyase	22	22
PL20	4.2.2.14	glucuronan lyase	2	2
PL21_1	4.2.2.7, 4.2.2.8, 4.2.2.-	heparin lyase, heparin-sulfate lyase	8	8
PL21	4.2.2.7, 4.2.2.8, 4.2.2.-	heparin lyase, heparin-sulfate lyase	17	17
PL22_1	4.2.2.6, 4.2.2.9	oligogalacturonide lyase, pectate disaccharide-lyase	6	6
PL22_2	—	—	49	49
PL22	4.2.2.6, 4.2.2.9	oligogalacturonide lyase, pectate disaccharide-lyase	167	164
PL24	4.2.2.-	—	56	44
PL25	4.2.2.-	—	37	35
PL26	4.2.2.24	rhamnogalacturonan exolyase	101	100
PL27	4.2.2.28	α-L-rhamnosyl-(1->4)-β-D-glucuronate lyase	4	4
PL28	4.2.2.-	—	22	19
PL29	4.2.2.1, 4.2.2.5, 4.2.2.19	hyaluronate lyase, chondroitin AC lyase, chondroitin B lyase	221	203
PL30	4.2.2.1	hyaluronate lyase	2	2
PL31	4.2.2.3, 4.2.2.14	mannuronate-specific alginate lyase, glucuronan lyase	49	48
PL33_1	4.2.2.1, 4.2.2.5, 4.2.2.19, 4.2.2.-	hyaluronate lyase, chondroitin AC lyase, chondroitin B lyase	68	68
PL33_2	4.2.2.5, 4.2.2.25	chondroitin AC lyase, gellan lyase	73	70
PL33	4.2.2.1, 4.2.2.5, 4.2.2.19, 4.2.2.25, 4.2.2.-	hyaluronate lyase, chondroitin AC lyase, chondroitin B lyase, gellan lyase	181	176
PL34	4.2.2.-	—	48	48
PL35	4.2.2.1, 4.2.2.8, 4.2.2.-	hyaluronate lyase, heparin-sulfate lyase	155	148
PL36_1	4.2.2.3	mannuronate-specific alginate lyase	4	4
PL36_2	4.2.2.3	mannuronate-specific alginate lyase	4	4
PL36	4.2.2.3	mannuronate-specific alginate lyase	8	8
PL37	4.2.2.5, 4.2.2.8, 4.2.2.-	chondroitin AC lyase, heparin-sulfate lyase	43	41
PL38	4.2.2.3, 4.2.2.11, 4.2.2.14, 4.2.2.-	mannuronate-specific alginate lyase, guluronate-specific alginate lyase, glucuronan lyase	249	236
PL39	4.2.2.3, 4.2.2.11, 4.2.2.-	mannuronate-specific alginate lyase, guluronate-specific alginate lyase	40	40
PL40	4.2.2.-	—	136	98
PL41	4.2.2.3	mannuronate-specific alginate lyase	16	16
PL42	4.2.2.28	α-L-rhamnosyl-(1->4)-β-D-glucuronate lyase	212	212
PL43	4.2.2.-	—	84	56
PL44	4.2.2.3	mannuronate-specific alginate lyase	23	21

CE Carbohydrate Esterases · 18 families and subfamilies · 21,541 genes · 20,686 CGCs

Family	EC numbers	Activity (EC name)	Genes	CGCs
CE1	2.3.1.122, 2.3.1.20, 3.1.1.-, 3.1.1.6, 3.1.1.72 (+1 more)	trehalose O-mycolyltransferase, diacylglycerol O-acyltransferase, acetylesterase, acetylxylan esterase (+1 more)	777	603
CE2	3.1.1.-, 3.1.1.6, 3.1.1.72	acetylesterase, acetylxylan esterase	228	226
CE3	3.1.1.6, 3.1.1.72	acetylesterase, acetylxylan esterase	104	103
CE4	3.1.1.6, 3.1.1.72, 3.5.1.-, 3.5.1.104, 3.5.1.41	acetylesterase, acetylxylan esterase, peptidoglycan-N-acetylglucosamine deacetylase, chitin deacetylase	2,366	2,340
CE5	3.1.1.3, 3.1.1.72, 3.1.1.74	triacylglycerol lipase, acetylxylan esterase, cutinase	143	100
CE6	3.1.1.72	acetylxylan esterase	181	180
CE7	3.1.1.-, 3.1.1.41, 3.1.1.72	cephalosporin-C deacetylase, acetylxylan esterase	472	466
CE8	3.1.1.11	pectinesterase	427	391
CE9	3.5.1.-, 3.5.1.25	N-acetylglucosamine-6-phosphate deacetylase	2,631	2,631
CE11	3.5.1.108	UDP-3-O-acyl-N-acetylglucosamine deacetylase	8,485	8,484
CE12	3.1.1.-, 3.1.1.6, 3.1.1.72, 3.1.1.86	acetylesterase, acetylxylan esterase, rhamnogalacturonan acetylesterase	529	458
CE14	3.5.1.-, 3.5.1.115, 3.5.1.33, 3.5.1.89	mycothiol S-conjugate amidase, N-acetylglucosamine deacetylase, N-acetylglucosaminylphosphatidylinositol deacetylase	2,000	2,000
CE15	3.1.1.117, 3.1.1.73	(4-O-methyl)-D-glucuronate--lignin esterase, feruloyl esterase	725	720
CE16	3.1.1.6	acetylesterase	29	29
CE17	3.1.1.-	—	65	65
CE19	3.1.1.11	pectinesterase	616	611
CE20	3.1.1.-, 3.1.1.53, 3.1.1.6, 3.1.1.72	sialate O-acetylesterase, acetylesterase, acetylxylan esterase	1,726	1,689
CE21	3.1.1.58	N-acetylgalactosaminoglycan deacetylase	37	35